Conditionally Immortalised Mesangial Cell Line

2 flasks of live human immortalized mesangial cell line. Mesangial cells form the central structural component of the glomerulus, with mesangial cell injury a characteristic of numerous renal diseases. Consequently, mesangial cells are a key therapeutic target in the treatment of human glomerular disease. Extensively characterised and published, these cells represent the most physiologically relevant model in which to study human glomerular disease in vitro, with the conditionally immortalised nature of the cell line enabling an in vitro process of differentiation equivalent to the in vivo differentiation of mesangial cells. Resulting cells express key mesangial markers including fibronectin, -smooth muscle actin and PDGF -R.

Please be aware:

• The cells arrive in 2 x T25 culture flasks, about 2 million cell/flask.
• These are live cells, not frozen.
• You will need an incubator and media ready for the arrival of the cells.
• Live cells are sent by FedEx but not dry ice shipping.
• Orders are prepared in batches (rather than preparing the cells for each collaborator individually) which may result in a delay of up to 2 months from payment date in sending the cells.
• During checkout, we ask that you provide us with any known closure dates/holidays over the next two months that mean you would be unable to receive the cells.
• During checkout, you will be asked to confirm that you have checked if import permission is required by your shipping destination, and arranged if necessary to do so.